Clinical Neurology by Greenberg David & Aminoff Michael & Simon Roger
Author:Greenberg, David & Aminoff, Michael & Simon, Roger [Greenberg, David]
Language: eng
Format: epub
Published: 0101-01-01T00:00:00+00:00
Clinical Findings
The disorder has its highest incidence in childhood. Initial symptoms often consist of headache, fever, and confusion; examination reveals signs of meningeal irritation. Multifocal neurologic deficits are common. The patient is typically encephalopathic, with disturbances of consciousness that range from somnolence to coma; seizures may occur. Flaccid weakness and sensory disturbance of the legs, extensor plantar responses, and urinary retention are common manifestations of spinal cord involvement. Other neurologic signs may indicate involvement of the optic nerves or cranial nerves, cerebral hemispheres, brainstem, or cerebellum; cerebellar ataxia is often conspicuous but optic neuritis, hemiparesis and other long-tract signs, aphasia, and even movement disorders may also occur.
The neurologic deficit resolves, at least in part, over a few weeks. Most patients make a virtually complete recovery, but some are left with severe residual deficits.
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